Multiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index.

Genetic studies have shown that obesity risk is heritable and that, of the many common variants now associated with body mass index, those in an intron of the fat mass and obesity-associated (FTO) gene have the largest effect. The size of the UK Biobank, and its joint measurement of genetic, anthrop...

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Autors principals: Young, A, Wauthier, F, Donnelly, P
Format: Journal article
Idioma:English
Publicat: Nature Publishing Group 2016