Stoichiometry and architecture of active DNA replication machinery in Escherichia coli.
The multiprotein replisome complex that replicates DNA has been extensively characterized in vitro, but its composition and architecture in vivo is unknown. Using millisecond single-molecule fluorescence microscopy in living cells expressing fluorescent derivatives of replisome components, we have e...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2010
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