Inhibition of fucosyl transferase and fucosidase by a rigid bicyclic mimic of alpha-L-fucose
A rigid bicyclic analogue of α-L-fucose, prepared from a monoacetonide of L-gulonolactone in an overall yield of 36% without the need for column chromatography, is a potent inhibitor of fucosidases and a weak inhibitor of a fucosyl transferase.
書誌詳細
| 主要な著者: |
Beacham, A,
Smelt, K,
Biggadike, K,
Britten, C,
Hackett, L,
Winchester, BG,
Nash, R,
Griffiths, R,
Fleet, G |
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| フォーマット: | Journal article
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| 言語: | English |
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| 出版事項: |
1998
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