Inhibition of fucosyl transferase and fucosidase by a rigid bicyclic mimic of alpha-L-fucose

Inhibition of fucosyl transferase and fucosidase by a rigid bicyclic mimic of alpha-L-fucose

A rigid bicyclic analogue of α-L-fucose, prepared from a monoacetonide of L-gulonolactone in an overall yield of 36% without the need for column chromatography, is a potent inhibitor of fucosidases and a weak inhibitor of a fucosyl transferase.

Dettagli Bibliografici
Autori principali:	Beacham, A, Smelt, K, Biggadike, K, Britten, C, Hackett, L, Winchester, BG, Nash, R, Griffiths, R, Fleet, G
Natura:	Journal article
Lingua:	English
Pubblicazione:	1998

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