Inhibition of fucosyl transferase and fucosidase by a rigid bicyclic mimic of alpha-L-fucose
A rigid bicyclic analogue of α-L-fucose, prepared from a monoacetonide of L-gulonolactone in an overall yield of 36% without the need for column chromatography, is a potent inhibitor of fucosidases and a weak inhibitor of a fucosyl transferase.
| Príomhchruthaitheoirí: | , , , , , , , , |
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| Formáid: | Journal article |
| Teanga: | English |
| Foilsithe / Cruthaithe: |
1998
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