Acclimatization of skeletal muscle mitochondria to high-altitude hypoxia during an ascent of Everest.

Acclimatization of skeletal muscle mitochondria to high-altitude hypoxia during an ascent of Everest.

Ascent to high altitude is associated with a fall in the partial pressure of inspired oxygen (hypobaric hypoxia). For oxidative tissues such as skeletal muscle, resultant cellular hypoxia necessitates acclimatization to optimize energy metabolism and restrict oxidative stress, with changes in gene a...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Levett, D, Radford, E, Menassa, D, Graber, E, Morash, A, Hoppeler, H, Clarke, K, Martin, D, Ferguson-Smith, A, Montgomery, H, Grocott, M, Murray, A
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	2012

Antzeko izenburuak

The effect of high-altitude on human skeletal muscle energetics: P-MRS results from the Caudwell Xtreme Everest expedition.
nork: Edwards, L, et al.
Argitaratua: (2010)

Oral Coenzyme Q10 supplementation does not prevent cardiac alterations during a high altitude trek to everest base cAMP.
nork: Holloway, C, et al.
Argitaratua: (2014)

Using modified Fenn diagrams to assess ventilatory acclimatization during ascent to high altitude: Effect of acetazolamide
nork: Rodion Isakovich, et al.
Argitaratua: (2024-07-01)

Cardiac response to hypobaric hypoxia: persistent changes in cardiac mass, function, and energy metabolism after a trek to Mt. Everest Base Camp.
nork: Holloway, C, et al.
Argitaratua: (2011)

New metric of hypoxic dose predicts altitude acclimatization status following various ascent profiles
nork: Beth A. Beidleman, et al.
Argitaratua: (2019-10-01)

Genome-Wide DNA Methylation Changes Associated With High-Altitude Acclimatization During an Everest Base Camp Trek
nork: Ainash Childebayeva, et al.
Argitaratua: (2021-06-01)

Steady‐state chemoreflex drive captures ventilatory acclimatization during incremental ascent to high altitude: Effect of acetazolamide
nork: Valerie C. Cates, et al.
Argitaratua: (2022-12-01)

Physiological responses during ascent to high altitude and the incidence of acute mountain sickness
nork: Cobb, AB, et al.
Argitaratua: (2021)

Design and conduct of Caudwell Xtreme Everest: an observational cohort study of variation in human adaptation to progressive environmental hypoxia
nork: Mythen Monty G, et al.
Argitaratua: (2010-10-01)

Caudwell Xtreme Everest: A prospective study of the effects of environmental hypoxia on cognitive functioning
nork: Griva, K, et al.
Argitaratua: (2017)

Neurovascular Coupling Remains Intact During Incremental Ascent to High Altitude (4240 m) in Acclimatized Healthy Volunteers
nork: Jack K. Leacy, et al.
Argitaratua: (2018-11-01)

The effect of high-altitude on human skeletal muscle energetics: P-MRS results from the Caudwell Xtreme Everest expedition.
nork: Lindsay M Edwards, et al.
Argitaratua: (2010-05-01)

Changes in lung function on ascent to altitude
nork: Pollard, A, et al.
Argitaratua: (1997)

Caudwell Xtreme Everest: A prospective study of the effects of environmental hypoxia on cognitive functioning.
nork: Konstadina Griva, et al.
Argitaratua: (2017-01-01)

Real-time electrocardiogram transmission from Mount Everest during continued ascent.
nork: Wei-Fong Kao, et al.
Argitaratua: (2013-01-01)

Does hypoxia play a role in the development of sarcopenia in humans? Mechanistic insights from the Caudwell Xtreme Everest Expedition
nork: Liesl Wandrag, et al.
Argitaratua: (2017-10-01)

Gut microbiota contributes to high-altitude hypoxia acclimatization of human populations
nork: Qian Su, et al.
Argitaratua: (2024-08-01)

Carry-Over Quality of Pre-acclimatization to Altitude Elicited by Intermittent Hypoxia: A Participant-Blinded, Randomized Controlled Trial on Antedated Acclimatization to Altitude
nork: Benedikt Treml, et al.
Argitaratua: (2020-05-01)

Sustained vasomotor control of skin microcirculation in Sherpas versus altitude‐naive lowlanders: Experimental evidence from Xtreme Everest 2
nork: Thomas Davies, et al.
Argitaratua: (2018-11-01)

Abnormal Cardiac High Energy Phosphate Metabolism and Impaired Diastolic Function after Mt Everest: A Reversible Model of Early Heart Failure?
nork: Holloway, C, et al.
Argitaratua: (2008)

Effect of intermittent normobaric hypoxia exposure on acclimatization to high altitude by air induction
nork: Gopinath Bhaumik, et al.
Argitaratua: (2021-10-01)

Effect of sildenafil and acclimatization on cerebral oxygenation at altitude.
nork: Chan, C, et al.
Argitaratua: (2005)

Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent
nork: Anren Song, et al.
Argitaratua: (2017-02-01)

Effects of ascent to high altitude on human antimycobacterial immunity.
nork: Sarah Eisen, et al.
Argitaratua: (2013-01-01)

AltitudeOmics: the integrative physiology of human acclimatization to hypobaric hypoxia and its retention upon reascent.
nork: Andrew W Subudhi, et al.
Argitaratua: (2014-01-01)

Mt Everest trek causes impaired cardiac high energy phosphate metabolism and diastolic impairment
nork: Montgomery Hugh, et al.
Argitaratua: (2009-01-01)

Effects of ascent to high altitude on human antimycobacterial immunity
nork: Eisen, S, et al.
Argitaratua: (2013)

Impact of high-altitude acclimatization and de-acclimatization on the intestinal microbiota of rats in a natural high-altitude environment
nork: Doudou Hao, et al.
Argitaratua: (2024-05-01)

DNA Methylation Changes Are Associated With an Incremental Ascent to High Altitude
nork: Ainash Childebayeva, et al.
Argitaratua: (2019-10-01)

Changes in labial capillary density on ascent to and descent from high altitude [version 1; referees: 2 approved]
nork: Edward Gilbert-Kawai, et al.
Argitaratua: (2016-08-01)

Altitude Acclimatization Alleviates the Hypoxia-Induced Suppression of Exogenous Glucose Oxidation During Steady-State Aerobic Exercise
nork: Andrew J. Young, et al.
Argitaratua: (2018-07-01)

Individual assessment of ventilatory acclimatization at high altitude
nork: Erik R. Swenson, et al.
Argitaratua: (2024-07-01)

THE EFFECT OF ACCLIMATIZATION ON THE HEART RATE TO INCREASED ALTITUDE
nork: Blaž Jereb, et al.
Argitaratua: (2010-09-01)

Structural modifications of the brain in acclimatization to high-altitude.
nork: Jiaxing Zhang, et al.
Argitaratua: (2010-01-01)

Design and conduct of Xtreme Everest 2: An observational cohort study of Sherpa and lowlander responses to graduated hypobaric hypoxia [v1; ref status: indexed, http://f1000r.es/57m]
nork: Edward Gilbert-Kawai, et al.
Argitaratua: (2015-04-01)

Effects on colour discrimination during long term exposure to high altitudes on Mt Everest.
nork: Willmann, G, et al.
Argitaratua: (2010)

Rehabilitation high altitude training program for Misi Perdana Everest UTM Climbers /
nork: Azham Afzanizam Hamzah, 1988-, author 573413, et al.
Argitaratua: (2017)

Rehabilitation high altitude training program for Misi Perdana Everest UTM Climbers /
nork: Azham Afzanizam Hamzah, 1988- , author 573413
Argitaratua: (2017)

The Use of Pulse Oximetry in the Assessment of Acclimatization to High Altitude
nork: Tobias Dünnwald, et al.
Argitaratua: (2021-02-01)

The role of microglia in neuronal and cognitive function during high altitude acclimatization
nork: Kathleen Hatch, et al.
Argitaratua: (2024-08-01)