Acclimatization of skeletal muscle mitochondria to high-altitude hypoxia during an ascent of Everest.

Acclimatization of skeletal muscle mitochondria to high-altitude hypoxia during an ascent of Everest.

Ascent to high altitude is associated with a fall in the partial pressure of inspired oxygen (hypobaric hypoxia). For oxidative tissues such as skeletal muscle, resultant cellular hypoxia necessitates acclimatization to optimize energy metabolism and restrict oxidative stress, with changes in gene a...

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Dettagli Bibliografici
Autori principali:	Levett, D, Radford, E, Menassa, D, Graber, E, Morash, A, Hoppeler, H, Clarke, K, Martin, D, Ferguson-Smith, A, Montgomery, H, Grocott, M, Murray, A
Natura:	Journal article
Lingua:	English
Pubblicazione:	2012

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