Epitope profiling using computational structural modelling demonstrated on coronavirus-binding antibodies

Identifying the epitope of an antibody is a key step in understanding its function and its potential as a therapeutic. Sequence-based clonal clustering can identify antibodies with similar epitope complementarity, however, antibodies from markedly different lineages but with similar structures can e...

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Bibliographic Details
Main Authors: Robinson, SA, Raybould, MIJ, Schneider, C, Wong, WK, Marks, C, Deane, CM
Format: Journal article
Language:English
Published: Public Library of Science 2021