Epitope profiling using computational structural modelling demonstrated on coronavirus-binding antibodies
Identifying the epitope of an antibody is a key step in understanding its function and its potential as a therapeutic. Sequence-based clonal clustering can identify antibodies with similar epitope complementarity, however, antibodies from markedly different lineages but with similar structures can e...
Main Authors: | Robinson, SA, Raybould, MIJ, Schneider, C, Wong, WK, Marks, C, Deane, CM |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2021
|
Similar Items
-
Epitope profiling using computational structural modelling demonstrated on coronavirus-binding antibodies.
by: Sarah A Robinson, et al.
Published: (2021-12-01) -
CoV-AbDab: the coronavirus antibody database
by: Raybould, MIJ, et al.
Published: (2020) -
Computationally profiling peptide: MHC recognition by T-cell receptors and T-cell receptor-mimetic antibodies
by: Raybould, MIJ, et al.
Published: (2023) -
Prospects for the computational humanization of antibodies and nanobodies
by: Gordon, GL, et al.
Published: (2024) -
Improved computational epitope profiling using structural models identifies a broader diversity of antibodies that bind to the same epitope
by: Fabian C. Spoendlin, et al.
Published: (2023-09-01)