Hydrogen bonding to hexafluoroisopropanol controls the oxidative strength of hypervalent iodine reagents
Hexafluoroisopropan-2-ol (HFIP) has been found to be an unusually beneficial solvent for undertaking hypervalent iodine-initiated [2+2] cycloaddition of styrenes. For the initiator phenyliodine(III) diacetate (PIDA), voltammetric data demonstrate that the enhanced reactivity in HFIP is due to its gr...
| Main Authors: | , , , , |
|---|---|
| Format: | Journal article |
| Published: |
American Chemical Society
2016
|