T cell responses to peptides covering the gag p24 region of HIV-1 occur in HIV-1 seronegative individuals.

We demonstrate that peptides (16 amino acids long) covering the sequence of the HIV-1 core protein p24 induce significant proliferation in peripheral blood mononuclear cells (PBMC) of several (greater than 50%) healthy seronegative volunteers as well as seronegative homosexual men. The nature of thi...

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Bibliographic Details
Main Authors: Vyakarnam, A, Matear, P, Cranenburg, C, Michie, C, Beverley, P, Wahren, B, Gill, S, Weller, I
Format: Journal article
Language:English
Published: 1991