Effects of transforming growth factor beta on megakaryocytic cell fusion and endomitosis.

Transforming growth factor beta (TGF-beta) is a cytokine secreted by megakaryocytes and platelets which inhibits the proliferation of megakaryocyte progenitors in vitro. We have studied the effects of TGF-beta on more mature megakaryocytes, using cell lines CMK, DAMI, and CHRF as well as isolated hu...

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Bibliographic Details
Main Authors: Cowley, S, Groopman, J, Avraham, H
Format: Journal article
Language:English
Published: 1992