NI-0801, an anti-chemokine (C-X-C motif) ligand 10 antibody, in patients with primary biliary cholangitis and an incomplete response to ursodeoxycholic acid

NI-0801 is a fully human monoclonal antibody against chemokine (C-X-C motif) ligand 10 (CXCL10), which is involved in the recruitment of inflammatory T cells into the liver. The safety and efficacy of NI-0801 was assessed in patients with primary biliary cholangitis. In this open-label phase 2a stud...

Full description

Bibliographic Details
Main Authors: de Graaf, K, Lapeyre, G, Guilhot, F, Ferlin, W, Curbishley, S, Carbone, M, Richardson, P, Moreea, S, McCune, C, Ryder, S, Chapman, R, Floreani, A, Jones, D, De Min, C, Adams, D, Invernizzi, P
Format: Journal article
Language:English
Published: Wiley 2018