Transforming growth factor-beta induces osteoclast formation in the absence of RANKL.

Transforming growth factor beta (TGFbeta) is a multifunctional growth factor that is produced by many cells in bone and is abundant in the bone matrix. TGFbeta is known to regulate RANKL-induced osteoclast formation and bone resorbing activity. In this study we sought to determine whether TGFbeta co...

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Bibliographic Details
Main Authors: Itonaga, I, Sabokbar, A, Sun, S, Kudo, O, Danks, L, Ferguson, D, Fujikawa, Y, Athanasou, N
Format: Journal article
Language:English
Published: 2004