Efficacy of a novel perfluorocarbon-based intrapulmonary drug delivery system

Introduction: We sought to determine the efficacy of a novel intrapulmonary perfluorocarbon (PFC) based antibiotic delivery system in a rat model of pneumococcal pneumonia. Methods: Wistar rats (400-500 g) were inoculated with 8x10' type 3 pneumococcus via direct intratracheal (IT) injection. T...

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Bibliographic Details
Main Authors: Dickson, E, Heard, S, Otto, S, Tarara, T, Brueggemann, A, Doem, G
Format: Journal article
Language:English
Published: 1998