Engineering synthetic signalling pathways with programmable dCas9-based chimeric receptors

Synthetic receptors provide a powerful experimental tool for generation of designer cells capable of monitoring the environment, sensing specific input signals, and executing diverse custom response programs. To advance the promise of cellular engineering, we have developed a class of chimeric recep...

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Bibliographic Details
Main Authors: Baeumler, T, Ahmed, A, Fulga, T
Format: Journal article
Published: Cell Press 2017