Investigations of an annulation-fragmentation-spirocyclisation approach to fawcettimine-type Lycopodium alkaloids

This paper reports progress in the development of a furan oxidative N-spirocyclisation approach to the fawcettimine alkaloids huperzine Q and lycopladine D. A short synthesis is described of a key intermediate cyclopentaindolizidine that subsequently fragments by N-acylation and β-elimination. The s...

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Detalles Bibliográficos
Main Authors: Seah, KY, Robertson, J
Formato: Journal article
Idioma:English
Publicado: Elsevier 2019