Pooled multicenter analysis of cardiovascular safety and population pharmacokinetic properties of piperaquine in African patients with uncomplicated falciparum Malaria

Dihydroartemisinin-piperaquine has shown excellent efficacy and tolerability in malaria treatment. However, concerns have been raised of potentially harmful cardiotoxic effects associated with piperaquine. The population pharmacokinetics and cardiac effects of piperaquine were evaluated in 1,000 pat...

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書誌詳細
主要な著者: Wattanakul, T, Ogutu, B, Kabanywanyi, AM, Asante, K-P, Oduro, A, Adjei, A, Sie, A, Sevene, E, Macete, E, Compaore, G, Valea, I, Osei, I, Winterberg, M, Gyapong, M, Adjuik, M, Abdulla, S, Owusu-Agyei, S, White, NJ, Day, NPJ, Tinto, H, Baiden, R, Binka, F, Tarning, J
フォーマット: Journal article
言語:English
出版事項: American Society for Microbiology 2020