Bisulfite-free direct detection of 5-methylcytosine and 5-hydroxymethylcytosine at base resolution

Bisulfite-free direct detection of 5-methylcytosine and 5-hydroxymethylcytosine at base resolution

Bisulfite sequencing has been the gold standard for mapping DNA modifications including 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) for decades1,2,3,4. However, this harsh chemical treatment degrades the majority of the DNA and generates sequencing libraries with low complexity2,5,6. H...

書誌詳細
主要な著者:	Liu, Y, Siejka-Zielinska, P, Velikova, G, Bi, Y, Yuan, F, Tomkova, M, Bai, C, Chen, L, Schuster-Boeckler, B, Song, C
フォーマット:	Journal article
出版事項:	Springer Nature 2019

類似資料

TAPS: a bisulfite-free, base-resolution and quantitative sequencing method for cytosine modifications
著者:: Liu, Y, 等
出版事項: (2019)

Subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution
著者:: Liu, Y, 等
出版事項: (2021)

Enzymatic approaches and bisulfite sequencing cannot distinguish between 5-methylcytosine and 5-hydroxymethylcytosine in DNA
著者:: Colm Nestor, 等
出版事項: (2010-04-01)

Bisulfite-free and base-resolution analysis of 5-methylcytidine and 5-hydroxymethylcytidine in RNA with peroxotungstate
著者:: Yuan, F, 等
出版事項: (2019)

Accurate measurement of 5-methylcytosine and 5-hydroxymethylcytosine in human cerebellum DNA by oxidative bisulfite on an array (OxBS-array).
著者:: Sarah F Field, 等
出版事項: (2015-01-01)

The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing.
著者:: Yun Huang, 等
出版事項: (2010-01-01)

5-hydroxymethylcytosine marks regions with reduced mutation frequency
著者:: Schuster-Boeckler, P, 等
出版事項: (2016)

5-hydroxymethylcytosine marks regions with reduced mutation frequency in human DNA.
著者:: Tomkova, M, 等
出版事項: (2016)

5-Methylcytosine and 5-Hydroxymethylcytosine Signatures Underlying Pediatric Cancers
著者:: Shalu Jhanwar, 等
出版事項: (2019-05-01)

5-Methylcytosine and 5-hydroxymethylcytosine spatiotemporal profiles in the mouse zygote.
著者:: Juliette Salvaing, 等
出版事項: (2012-01-01)

5-hydroxymethylcytosine marks regions with reduced mutation frequency in human DNA
著者:: Marketa Tomkova, 等
出版事項: (2016-05-01)

Distribution of 5-methylcytosine and 5-hydroxymethylcytosine in bovine fetal tissue of the placenta
著者:: Anelise S. Mendonça, 等

Whole-Genome Sequencing of 5‑Hydroxymethylcytosine at Base Resolution by Bisulfite-Free Single-Step Deamination with Engineered Cytosine Deaminase
著者:: Neng-Bin Xie, 等
出版事項: (2023-11-01)

Double and single stranded detection of 5-methylcytosine and 5-hydroxymethylcytosine with nanopore sequencing
著者:: Dominic Oliver Halliwell, 等
出版事項: (2025-02-01)

5'-Methylcytosine and 5'-hydroxymethylcytosine each provide epigenetic information to the mouse zygote.
著者:: Yan Li, 等
出版事項: (2013-01-01)

Characterization of 5-methylcytosine and 5-hydroxymethylcytosine in human placenta cell types across gestation
著者:: Rebecca L. Wilson, 等
出版事項: (2019-07-01)

A Novel Application of Mixed Effects Models for Reconciling Base-Pair Resolution 5-Methylcytosine and 5-Hydroxymethylcytosine Data in Neuroepigenetics
著者:: Joseph Kochmanski, 等
出版事項: (2019-09-01)

Development of bisulfite-free DNA methylation sequencing methods and their application to cell-free DNA for cancer detection
著者:: Siejka-Zielinska, P
出版事項: (2020)

TET2 mutations are associated with specific 5-methylcytosine and 5-hydroxymethylcytosine profiles in patients with chronic myelomonocytic leukemia
著者:: Pérez, C, 等
出版事項: (2012)

TET2 mutations are associated with specific 5-methylcytosine and 5-hydroxymethylcytosine profiles in patients with chronic myelomonocytic leukemia.
著者:: Cristina Pérez, 等
出版事項: (2012-01-01)

Optimized bisulfite sequencing analysis reveals the lack of 5-methylcytosine in mammalian mitochondrial DNA
著者:: Zhenyu Shao, 等
出版事項: (2023-08-01)

Association of tet methylcytosine dioxygenase 2 and 5-hydroxymethylcytosine in endometrioid adenocarcinoma and its clinical significance
著者:: Lei Kuang, 等
出版事項: (2024-03-01)

The recognition, generation and detection of 5-hydroxymethylcytosine
著者:: Bi, Y
出版事項: (2020)

Quantitation and mapping of the epigenetic marker 5-hydroxymethylcytosine
著者:: Qing, Y, 等
出版事項: (2017)

DNA repair enzymes ALKBH2, ALKBH3, and AlkB oxidize 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine in vitro
著者:: Bian, Ke, 等
出版事項: (2020)

Use of a Single Sequencing Termination Reaction to Distinguish Between Cytosine and 5-Methylcytosine in Bisulfite-Modified DNA
著者:: Zhou Yuanxiang, 等
出版事項: (1997-05-01)

Dysregulation and prognostic potential of 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) levels in prostate cancer
著者:: Tine Maj Storebjerg, 等
出版事項: (2018-08-01)

Oxygenase catalyzed 5-methylcytosine hydroxylation.
著者:: Loenarz, C, 等
出版事項: (2009)

Modular oxidation of cytosine modifications and their application in direct and quantitative sequencing of 5-hydroxymethylcytosine
著者:: Xu, H, 等
出版事項: (2023)

Cell-Free DNA 5-Hydroxymethylcytosine Signatures for Lung Cancer Prognosis
著者:: Jianming Shao, 等
出版事項: (2024-02-01)

5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages
著者:: Song, C, 等
出版事項: (2017)

5-Hydroxymethylcytosine Loss in Conjunctival Melanoma
著者:: Alexandre Stahl, 等
出版事項: (2021-06-01)

Base resolution maps reveal the importance of 5-hydroxymethylcytosine in a human glioblastoma
著者:: Eun-Ang Raiber, 等
出版事項: (2017-03-01)

5-Hydroxymethylcytosine (5-hmC) Specific Enrichment
著者:: Keith Szulwach, 等
出版事項: (2012-08-01)

Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain.
著者:: Condliffe, D, 等
出版事項: (2014)

Directionality of point mutation and 5-methylcytosine deamination rates in the chimpanzee genome
著者:: Zhao Zhongming, 等
出版事項: (2006-12-01)

Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain
著者:: Condliffe, D, 等
出版事項: (2014)

5-Hydroxymethylcytosine profilings in circulating cell-free DNA as diagnostic biomarkers for DLBCL
著者:: Hangyu Chen, 等
出版事項: (2024-11-01)

5-Hydroxymethylcytosine in Cell-Free DNA Predicts Immunotherapy Response in Lung Cancer
著者:: Jianming Shao, 等
出版事項: (2024-04-01)

Cell‐free DNA 5‐hydroxymethylcytosine as a marker for common cancer detection
著者:: Jianming Shao, 等
出版事項: (2022-12-01)