Glucose analogue inhibitors of glycogen phosphorylase: the design of potential drugs for diabetes.
The T-state crystal structure of the glucose-phosphorylase b complex has been used as a model for the design of glucose analogue inhibitors that may be effective in the regulation of blood glucose levels. Modeling studies indicated room for additional atoms attached at the C1-beta position of glucos...
Egile Nagusiak: | Martin, J, Veluraja, K, Ross, K, Johnson, L, Fleet, G, Ramsden, N, Bruce, I, Orchard, MG, Oikonomakos, N, Papageorgiou, A |
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Formatua: | Journal article |
Hizkuntza: | English |
Argitaratua: |
1991
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