Glucose analogue inhibitors of glycogen phosphorylase: the design of potential drugs for diabetes.

Glucose analogue inhibitors of glycogen phosphorylase: the design of potential drugs for diabetes.

The T-state crystal structure of the glucose-phosphorylase b complex has been used as a model for the design of glucose analogue inhibitors that may be effective in the regulation of blood glucose levels. Modeling studies indicated room for additional atoms attached at the C1-beta position of glucos...

Полное описание

Библиографические подробности
Главные авторы:	Martin, J, Veluraja, K, Ross, K, Johnson, L, Fleet, G, Ramsden, N, Bruce, I, Orchard, MG, Oikonomakos, N, Papageorgiou, A
Формат:	Journal article
Язык:	English
Опубликовано:	1991

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