Store-operated cyclic AMP signalling mediated by STIM1.

Depletion of Ca(2+) from the endoplasmic reticulum (ER) results in activation of plasma membrane Ca(2+) entry channels. This 'store-operated' process requires translocation of a transmembrane ER Ca(2+) sensor protein, stromal interaction molecule 1 (STIM1), to sites closely apposed to Ca(2...

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Autors principals: Lefkimmiatis, K, Srikanthan, M, Maiellaro, I, Moyer, M, Curci, S, Hofer, A
Format: Journal article
Idioma:English
Publicat: 2009