Polypyrimidine tract binding protein 1 regulates the activation of mouse CD8 T cells

The RNA-binding protein polypyrimidine tract binding protein 1 (PTBP1) has been found to have roles in CD4 T-cell activation, but its function in CD8 T cells remains untested. We show it is dispensable for the development of naïve mouse CD8 T cells, but is necessary for the optimal expansion and pro...

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Bibliographic Details
Main Authors: D'Angeli, V, Monzón-Casanova, E, Matheson, LS, Gizlenci, Ö, Petkau, G, Gooding, C, Berrens, RV, Smith, CWJ, Turner, M
Format: Journal article
Language:English
Published: Wiley 2022