Computational analysis of the number, area and density of gamma-H2AX foci in breast cancer cells exposed to (111)In-DTPA-hEGF or gamma-rays using Image-J software.

PURPOSE: To develop a simple method for the quantification of gamma-H2AX focus number, density and size. METHODS: MDA-MB-468 human breast cancer cells were treated overnight with (111)In-diethylenetriaminepentaacetic acid human epidermal growth factor ((111)In-DTPA-hEGF, 0-142 kBq/pmol) or exposed t...

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Bibliographic Details
Main Authors: Cai, Z, Vallis, K, Reilly, R
Format: Journal article
Language:English
Published: 2009