Acute increases in serum creatinine after starting angiotensin-converting enzyme inhibitor-based therapy and effects of its continuation on major clinical outcomes in type 2 diabetes mellitus: the ADVANCE trial

Acute increases in serum creatinine after starting angiotensin-converting enzyme inhibitor-based therapy and effects of its continuation on major clinical outcomes in type 2 diabetes mellitus: the ADVANCE trial

Discontinuation of angiotensin-converting enzyme (ACE) inhibitor is recommended if patients experience ≥30% acute increase in serum creatinine after starting this therapy. However, the long-term effects of its continuation or discontinuation on major clinical outcomes after increases in serum creati...

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Bibliographic Details
Main Authors: Ohkuma, T, Jun, M, Rodgers, A, Cooper, M, Glasziou, P, Hamet, P, Harrap, S, Mancia, G, Marre, M, Neal, B, Perkovic, V, Poulter, N, Williams, B, Zoungas, S, Chalmers, J, Woodward, M, on behalf of the ADVANCE Collaborative Group
Format: Journal article
Published: American Heart Association 2018

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