A peptide filtering relation quantifies MHC class I peptide optimization.

Major Histocompatibility Complex (MHC) class I molecules enable cytotoxic T lymphocytes to destroy virus-infected or cancerous cells, thereby preventing disease progression. MHC class I molecules provide a snapshot of the contents of a cell by binding to protein fragments arising from intracellular...

Full description

Bibliographic Details
Main Authors: Dalchau, N, Phillips, A, Goldstein, L, Howarth, M, Cardelli, L, Emmott, S, Elliott, T, Werner, J
Format: Journal article
Language:English
Published: 2011