VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment.

Lymphangiogenesis, an important initial step in tumor metastasis and transplant sensitization, is mediated by the action of VEGF-C and -D on VEGFR3. In contrast, VEGF-A binds VEGFR1 and VEGFR2 and is an essential hemangiogenic factor. We re-evaluated the potential role of VEGF-A in lymphangiogenesis...

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Váldodahkkit: Cursiefen, C, Chen, L, Borges, L, Jackson, D, Cao, J, Radziejewski, C, D'Amore, P, Dana, MR, Wiegand, S, Streilein, J
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2004