A transmission-virulence evolutionary trade-off explains attenuation of HIV-1 in Uganda
Evolutionary theory hypothesizes that intermediate virulence maximizes pathogen fitness as a result of a trade-off between virulence and transmission, but empirical evidence remains scarce. We bridge this gap using data from a large and long-standing HIV-1 prospective cohort, in Uganda. We use an ep...
| Principais autores: | , , , , , , , , , , , , , , |
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| Formato: | Journal article |
| Publicado em: |
eLife Sciences Publications
2016
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