The antimalarial effect of iron chelators: studies in animal models and in humans with mild falciparum malaria.

In this study we explore the antimalarial effects of 3-hydroxypyridin-4-ones (CP compounds), a family of bidentate orally effective iron chelators in experimental animal systems in vivo and in vitro, and examine whether the iron chelator deferoxamine (DF) is active against human infection with P. fa...

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Bibliographic Details
Main Authors: Hershko, C, Gordeuk, V, Thuma, P, Theanacho, E, Spira, D, Hider, R, Peto, T, Brittenham, G
Format: Journal article
Language:English
Published: 1992