Desmopressin normalizes the blunted adrenocorticotropin response to corticotropin-releasing hormone in melancholic depression: evidence of enhanced vasopressinergic responsivity.

Major depression is associated with significant disturbance in hypothalamic-pituitary-adrenal axis functioning, including blunted release of ACTH in response to CRH infusion. Eight melancholic depressives and eight matched healthy comparison subjects underwent, in random order, the following challen...

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Bibliographic Details
Main Authors: Dinan, T, Lavelle, E, Scott, L, Newell-Price, J, Medbak, S, Grossman, AB
Format: Journal article
Language:English
Published: 1999