HIV-1 variation diminishes CD4 T lymphocyte recognition.
Effective long-term antiviral immunity requires specific cytotoxic T lymphocytes and CD4(+) T lymphocyte help. Failure of these helper responses can be a principle cause of viral persistence. We sought evidence that variation in HIV-1 CD4(+) T helper epitopes might contribute to this phenomenon. To...
| Main Authors: | , , , , |
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| Format: | Conference item |
| Published: |
1998
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