Nucleotide and haplotypic diversity of the NOS2A promoter region and its relationship to cerebral malaria.

To assess the hypothesis that nitric oxide is critical in the pathogenesis of cerebral malaria, we analysed genetic variation in the proximal promoter region of NOS2A, the gene encoding inducible nitric oxide synthase. Sequencing 72 Gambian chromosomes revealed 11 single nucleotide polymorphisms in...

Full description

Bibliographic Details
Main Authors: Burgner, D, Usen, S, Rockett, K, Jallow, M, Ackerman, H, Cervino, A, Pinder, M, Kwiatkowski, D
Format: Journal article
Language:English
Published: 2003