Requirement for endocytic antigen processing and influence of invariant chain and H-2M deficiencies in CNS autoimmunity.

The role of processing in antigen (Ag) presentation and T cell activation in experimental allergic encephalomyelitis (EAE) was evaluated in wild-type mice, mice that selectively express either Ii p31 or p41, and mice completely deficient in Ii or H-2M. We demonstrate that processing of myelin oligod...

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Hlavní autoři: Slavin, A, Soos, J, Stuve, O, Patarroyo, J, Weiner, H, Fontana, A, Bikoff, E, Zamvil, S
Médium: Journal article
Jazyk:English
Vydáno: 2001