Protein and gene expression of tumour necrosis factor receptors I and II and their promoter gene polymorphisms in Alzheimer's disease.

The levels of pro-inflammatory cytokines, such as tumour necrosis factor-alpha (TNF-alpha), are increased in the brain in Alzheimer's disease (AD). Most of the biological properties of TNF-alpha are mediated through its two receptors, tumour necrosis factor receptors I and II (TNF-RI and TNF-RI...

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Bibliographic Details
Main Authors: Culpan, D, Cornish, A, Love, S, Kehoe, P, Wilcock, G
Format: Journal article
Language:English
Published: 2007