The Transcellular Propagation and Intracellular Trafficking of α-Synuclein
Parkinson’s disease is the second most common neurodegenerative disorder, with only partial symptomatic therapy and no mechanism-based therapies. The accumulation and aggregation of α-synuclein is causatively linked to the sporadic form of the disease, which accounts for 95% of cases. The pathology...
Main Authors: | Tofaris, GK, Goedert, M, Spillantini, MG |
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Format: | Journal article |
Published: |
Cold Spring Harbor Laboratory Press
2016
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