The link module from ovulation- and inflammation-associated protein TSG-6 changes conformation on hyaluronan binding.

The solution structure of the Link module from human TSG-6, a hyaladherin with important roles in inflammation and ovulation, has been determined in both its free and hyaluronan-bound conformations. This reveals a well defined hyaluronan-binding groove on one face of the Link module that is closed i...

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Autori principali: Blundell, C, Mahoney, D, Almond, A, DeAngelis, P, Kahmann, J, Teriete, P, Pickford, A, Campbell, I, Day, A
Natura: Journal article
Lingua:English
Pubblicazione: 2003