Enzyme-free synthesis of cyclic single-stranded DNA constructs containing a single triazole, amide or phosphoramidate backbone linkage and their use as templates for rolling circle amplification and nanoflower formation

Cyclic oligonucleotides are valuable targets with a broad range of potential applications spanning molecular biology and nanotechnology. Of particular importance is their role as templates in the rolling circle amplification (RCA) reaction. We describe three different chemical cyclisation methods fo...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Chen, J, Baker, Y, Brown, A, El-Sagheer, A, Brown, T
Formatua: Journal article
Argitaratua: Royal Society of Chemistry 2018