HLA class I-driven evolution of human immunodeficiency virus type 1 subtype c proteome: immune escape and viral load.

Human immunodeficiency virus type 1 (HIV-1) mutations that confer escape from cytotoxic T-lymphocyte (CTL) recognition can sometimes result in lower viral fitness. These mutations can then revert upon transmission to a new host in the absence of CTL-mediated immune selection pressure restricted by t...

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Bibliographic Details
Main Authors:	Rousseau, C, Daniels, MG, Carlson, J, Kadie, C, Crawford, H, Prendergast, A, Matthews, P, Payne, R, Rolland, M, Raugi, D, Maust, B, Learn, G, Nickle, D, Coovadia, H, Ndung'u, T, Frahm, N, Brander, C, Walker, B, Goulder, P, Bhattacharya, T, Heckerman, D, Korber, B, Mullins, J
Format:	Journal article
Language:	English
Published:	2008

HLA class I-driven evolution of human immunodeficiency virus type 1 subtype c proteome: immune escape and viral load.

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