Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse

The recognition events that mediate adaptive cellular immunity and regulate antibody responses depend on intercellular contacts between T cells and antigen-presenting cells (APCs). T-cell signalling is initiated at these contacts when surface-expressed T-cell receptors (TCRs) recognize peptide fragm...

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Bibliographic Details
Main Authors: Choudhuri, K, Llodrá, J, Roth, E, Tsai, J, Gordo, S, Wucherpfennig, K, Kam, L, Stokes, D, Dustin, M
Format: Journal article
Language:English
Published: Nature Publishing Group 2014