Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse
The recognition events that mediate adaptive cellular immunity and regulate antibody responses depend on intercellular contacts between T cells and antigen-presenting cells (APCs). T-cell signalling is initiated at these contacts when surface-expressed T-cell receptors (TCRs) recognize peptide fragm...
Main Authors: | Choudhuri, K, Llodrá, J, Roth, E, Tsai, J, Gordo, S, Wucherpfennig, K, Kam, L, Stokes, D, Dustin, M |
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Format: | Journal article |
Language: | English |
Published: |
Nature Publishing Group
2014
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