The effects of an IL-21 receptor antagonist on the alloimmune response in a humanized mouse skin transplant model

<br/><strong>Background: </strong>Interleukin 21 (IL-21) is involved in regulating the expansion and effector function of a broad range of leukocytes, including T cells and B cells. In transplantation, the exact role of IL-21 in the process of allograft rejection is unknown. To fur...

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Bibliographic Details
Main Authors: De Leur, K, Luk, F, Van Den Bosch, T, Dieterich, M, Van Der Laan, L, Hendriks, R, Groningen, C, Issa, F, Baan, C, Hoogduijn, M
Format: Journal article
Language:English
Published: Lippincott, Williams & Wilkins 2019