Ac/Ds transposition for CRISPR/dCas9-SID4x epigenome modulation in zebrafish

Due to its genetic amenability coupled with advances in genome editing, zebrafish is an excellent model to examine the function of (epi)genomic elements. Here, we repurposed the Ac/Ds maize transposition system to efficiently characterise zebrafish cis-regulated elements, also known as enhancers, in...

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Bibliographic Details
Main Authors: Chong-Morrison, V, Mayes, S, Simões, FC, Senanayake, U, Carroll, DS, Riley, PR, Wilson, SW, Sauka-Spengler, T
Format: Journal article
Language:English
Published: Company of Biologists 2023