An ancestral Ashkenazi haplotype at the HMPS/CRAC1 locus on 15q13-q14 is associated with hereditary mixed polyposis syndrome.

The putative locus for hereditary mixed polyposis syndrome (HMPS) in a large family of Ashkenazi descent (SM96) was previously reported to map to chromosome sub-bands 6q16-q21. However, new clinical data, together with molecular data from additional family members, have shown 6q linkage to be incorr...

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Bibliographic Details
Main Authors:	Jaeger, E, Woodford-Richens, K, Lockett, M, Rowan, A, Sawyer, E, Heinimann, K, Rozen, P, Murday, V, Whitelaw, S, Ginsberg, A, Atkin, W, Lynch, H, Southey, M, Debinski, H, Eng, C, Bodmer, W, Talbot, I, Hodgson, S, Thomas, H, Tomlinson, I
Format:	Journal article
Language:	English
Published:	2003

An ancestral Ashkenazi haplotype at the HMPS/CRAC1 locus on 15q13-q14 is associated with hereditary mixed polyposis syndrome.

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