HIGHLY ENANTIOSELECTIVE REARRANGEMENT OF A MESO-EPOXIDE TO AN ALLYL ALCOHOL FOR CARBOCYCLIC NUCLEOSIDE SYNTHESIS - AN INTERNAL ALKOXIDE EFFECT
The synthesis of the enantiomeric cis-4-(hydroxymethyl)cyclopent-2-ene-1-ols 2 and 3 (R = H) via a highly enantioselective rearrangement of cis-6-oxabicyclo[3.1.0]hexane-3-methanol 4 (R = H) using the dilithium salts of(+)- or (-)-norephedrine is described. © 1994.
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1994
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