Is JmjC oxygenase catalysis limited to demethylation?

Jobs on the side: Substrate selectivity studies indicate that members of the biomedically important JmjC demethylase family of histone N(ε)-methyllysine demethylases are capable of catalyzing the de-N-alkylation of groups other than N-methyl and can catalyze reactions that form stable hydroxylated p...

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Dettagli Bibliografici
Autori principali: Hopkinson, R, Walport, L, Münzel, M, Rose, N, Smart, T, Kawamura, A, Claridge, T, Schofield, C
Natura: Journal article
Lingua:English
Pubblicazione: 2013