Is JmjC oxygenase catalysis limited to demethylation?

Jobs on the side: Substrate selectivity studies indicate that members of the biomedically important JmjC demethylase family of histone N(ε)-methyllysine demethylases are capable of catalyzing the de-N-alkylation of groups other than N-methyl and can catalyze reactions that form stable hydroxylated p...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Hopkinson, R, Walport, L, Münzel, M, Rose, N, Smart, T, Kawamura, A, Claridge, T, Schofield, C
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2013