Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila.

The membrane proteins Star and Rhomboid-1 have been genetically defined as the primary regulators of EGF receptor activation in Drosophila, but their molecular mechanisms have been elusive. Both Star and Rhomboid-1 have been assumed to work at the cell surface to control ligand activation. Here, we...

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Hlavní autoři: Lee, JR, Urban, S, Garvey, C, Freeman, M
Médium: Journal article
Jazyk:English
Vydáno: 2001