Quantification of mRNA in single cells and modelling of RT-qPCR induced noise

<p style="text-align:justify;"> <b>Background:</b> Gene expression has a strong stochastic element resulting in highly variable mRNA levels between individual cells, even in a seemingly homogeneous cell population. Access to fundamental information about cellular mechani...

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Bibliographic Details
Main Authors: Bengtsson, M, Hemberg, M, Rorsman, P, Ståhlberg, A
Format: Journal article
Language:English
Published: BioMed Central 2008