Temperature regulates NF-κB dynamics and function through timing of A20 transcription

NF-κB signaling plays a pivotal role in control of the inflammatory response. We investigated how the dynamics and function of NF-κB were affected by temperature within the mammalian physiological range (34 °C to 40 °C). An increase in temperature led to an increase in NF-κB nuclear/cytoplasmic osci...

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Bibliographic Details
Main Authors: Harper, C, Woodcock, D, Lam, C, Garcia-Albornoz, M, Adamson, A, Ashall, L, Rowe, W, Downton, P, Schmidt, L, West, S, Spiller, D, Rand, D, White, M
Format: Journal article
Published: National Academy of Sciences 2018