The regulation of interleukin-8 by hypoxia in human macrophages--a potential role in the pathogenesis of the acute respiratory distress syndrome (ARDS).

BACKGROUND: The acute respiratory distress syndrome (ARDS) represents a form of severe acute inflammatory lung disease. We have previously demonstrated significantly raised interleukin-8 (IL-8) levels in the lungs of at-risk patients that progress to ARDS, and identified the alveolar macrophage as a...

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Bibliographic Details
Main Authors: Hirani, N, Antonicelli, F, Strieter, R, Wiesener, MS, Ratcliffe, P, Haslett, C, Donnelly, S
Format: Journal article
Language:English
Published: 2001